"Heart and Soul" is a popular song composed by Hoagy Carmichael with lyrics by Frank Loesser... It charted with different artists between 1938 and 1961... The Cleftones succeeded with a rhythm and blues rearrangement of the song in 1961... After the release on April 17, 1961, "Heart and Soul" reached number 18 on the Billboard Hot 100 in July of that year, making this song The Cleftones' most popular work...